Melchior M1, Ziad A2, Courtin E3,4, Goldberg M2, Zins M2, van der Waerden J1.
1 Sorbonne Université, Université Pierre et Marie Curie, Institut National de la Santé et de la Recherche Médicale, Institut Pierre Louis d'Epidémiologie et de Santé Publique UMRS 1136, Paris, France.
2 Population-Based Epidemiological Cohorts Unit, Institut National de la Santé et de la Recherche Médicale UMS 11, Villejuif, France.
3 Department of Social Policy, LSE Health and Social Care, London School of Economics and Political Science, London, United Kingdom.
4 Department of Social Science, Health and Medicine, King's College London, London, United Kingdom.
Am J Epidemiol. 2018 Feb 1;187(2):260-269. doi: 10.1093/aje/kwx252.
1 Sorbonne Université, Université Pierre et Marie Curie, Institut National de la Santé et de la Recherche Médicale, Institut Pierre Louis d'Epidémiologie et de Santé Publique UMRS 1136, Paris, France.
2 Population-Based Epidemiological Cohorts Unit, Institut National de la Santé et de la Recherche Médicale UMS 11, Villejuif, France.
3 Department of Social Policy, LSE Health and Social Care, London School of Economics and Political Science, London, United Kingdom.
4 Department of Social Science, Health and Medicine, King's College London, London, United Kingdom.
Am J Epidemiol. 2018 Feb 1;187(2):260-269. doi: 10.1093/aje/kwx252.
Abstract
Using
data from the nationally representative Consultants des Centres
d'Examens de Santé (CONSTANCES) study in France (2012-2014; n = 67,057),
we assessed the relationship between intergenerational socioeconomic
mobility and adult depression (Center for Epidemiological
Studies-Depression Scale scores of ≥16 in men or ≥20 in women) and
antidepressant use. Socioeconomic position was ascertained by
occupational grade (childhood: maternal and paternal measures prior to
age 15 years combined; adulthood: participant's own). We used logistic
regression models adjusted for sociodemographic characteristics,
parental history of psychiatric disorders and suicide, health behaviors,
and chronic health problems. Compared with the reference group
(persistently high socioeconomic circumstances), participants in other
groups had elevated levels of depression (for upward mobility,
multivariate odds ratios (OR) = 1.21; intermediate socioeconomic
position, 1.28; downward mobility, 1.66; persistently low socioeconomic
position, 1.82). Downward mobility and persistently low socioeconomic
position were also associated with elevated odds of antidepressant use
(for downward mobility, multivariate OR = 1.24; for persistently low
socioeconomic position, 1.36). In supplementary analyses, the
association of socioeconomic mobility with depression was stronger in
women than in men and among younger participants (aged 18-29 years) than
among older participants. Factors that contribute to depression risk
and socioeconomic inequalities in this area appeared to be at play
already in childhood; this should be acknowledged by clinicians and
policymakers.
https://academic.oup.com/aje/article-abstract/187/2/260/3883632?redirectedFrom=fulltext
https://academic.oup.com/aje/article-abstract/187/2/260/3883632?redirectedFrom=fulltext